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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0664
All Species:
33.94
Human Site:
Y517
Identified Species:
62.22
UniProt:
O75153
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75153
NP_056044.3
1309
146670
Y517
T
V
V
S
H
P
R
Y
L
E
L
L
E
R
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548323
1501
166268
Y709
T
V
M
S
H
P
R
Y
L
E
L
L
E
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW19
1315
148050
Y517
T
V
V
S
H
P
R
Y
L
E
L
L
E
R
T
Rat
Rattus norvegicus
XP_001080615
1352
151608
Y558
T
V
V
S
H
P
R
Y
L
E
L
L
E
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509391
982
108607
F293
M
F
I
W
N
N
I
F
F
S
L
G
F
D
V
Chicken
Gallus gallus
XP_415920
1293
145294
Y553
T
V
V
S
H
P
K
Y
L
E
L
L
E
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A0JMD0
1400
155792
Y562
T
V
V
S
H
P
K
Y
L
E
L
L
E
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAB5
1448
160833
Y606
T
V
L
S
H
P
K
Y
L
E
L
L
R
Q
A
Honey Bee
Apis mellifera
XP_624898
1290
145677
Y538
T
V
L
T
H
P
K
Y
L
E
L
L
N
K
T
Nematode Worm
Caenorhab. elegans
P34466
1247
139903
Y516
T
V
V
S
D
E
K
Y
H
E
L
L
E
D
A
Sea Urchin
Strong. purpuratus
XP_001198284
1101
124381
L412
R
K
N
L
P
E
R
L
L
R
E
R
A
I
F
Poplar Tree
Populus trichocarpa
XP_002314020
1343
146561
F507
K
I
C
W
N
E
D
F
H
S
K
V
V
E
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RY84
1211
135142
E473
E
N
K
R
H
D
L
E
A
S
V
E
M
K
G
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.3
N.A.
94.9
89.9
N.A.
60.8
83.1
N.A.
75
N.A.
52
59.8
39.9
51.9
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
96.9
92.7
N.A.
67.2
89.3
N.A.
83.6
N.A.
69
75.7
59.5
63.7
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
6.6
86.6
N.A.
86.6
N.A.
66.6
66.6
60
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
26.6
100
N.A.
100
N.A.
86.6
93.3
66.6
13.3
Percent
Protein Identity:
27.3
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
48.9
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
24
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
8
0
0
0
0
0
0
16
0
% D
% Glu:
8
0
0
0
0
24
0
8
0
70
8
8
54
8
0
% E
% Phe:
0
8
0
0
0
0
0
16
8
0
0
0
8
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% G
% His:
0
0
0
0
70
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
8
8
8
0
0
0
39
0
0
0
8
0
0
31
0
% K
% Leu:
0
0
16
8
0
0
8
8
70
0
77
70
0
0
0
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
8
0
16
8
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
62
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
8
0
0
39
0
0
8
0
8
8
31
0
% R
% Ser:
0
0
0
62
0
0
0
0
0
24
0
0
0
0
0
% S
% Thr:
70
0
0
8
0
0
0
0
0
0
0
0
0
0
54
% T
% Val:
0
70
47
0
0
0
0
0
0
0
8
8
8
0
8
% V
% Trp:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _